Nutrient Combo Test

Vitamin D, also known as the "sunshine vitamin", is central to numerous physiological processes in the body. There are two main forms: Vitamin D2, which is found in plant sources such as mushrooms, and Vitamin D3, which is produced in the skin through sunlight. Both forms can also be obtained through diet or dietary supplements.

Vitamin D is particularly important for the health of bones and teeth, as it promotes the absorption and utilisation of calcium and phosphorus. Furthermore, it strengthens the immune system and supports cell growth. A deficiency in vitamin D can lead to osteoporosis, a weakened immune system and increased susceptibility to infections, which is why adequate intake is essential.

Vitamin B9, known as folic acid in its synthetic form or folate in its natural form, is an essential B vitamin that is vital for the human organism. As it belongs to the water-soluble vitamins and the body cannot store it, it must be regularly obtained through the diet, as it cannot be produced by the body itself.

Vitamin B9 plays a crucial role in many bodily functions, including the production and repair of DNA as well as cell division and cell growth. Folic acid is particularly essential during pregnancy, as it contributes to the healthy development of the foetus and reduces the risk of neural tube defects.

It is also necessary for the formation of red blood cells and helps prevent anaemia and associated symptoms such as dizziness. A deficiency in folic acid can lead to serious health problems, which is why adequate intake of this vitamin is of great importance.

Magnesium is an essential mineral and one of the most important electrolytes in the human body. It plays a central role in numerous physiological functions that are essential for maintaining health and well-being.

Magnesium is involved in over 300 enzymatic reactions, including energy production, muscle and nerve function, and the synthesis of proteins and DNA. A large proportion of magnesium is stored in the bones and contributes to the stability and strength of the skeleton.

Furthermore, magnesium serves as a cofactor for many enzymes involved in essential biochemical processes such as protein synthesis, DNA repair, and blood sugar regulation.

It plays a crucial role in nerve impulse transmission and the regulation of neurotransmitters that enable communication between nerve cells. It also helps stabilise the electrolyte balance, which is essential for fluid regulation and normal cell function.

Vitamin B12, also known as cobalamin, is an essential, water-soluble vitamin that is indispensable for numerous important bodily functions. As the body cannot produce vitamin B12 itself, it must be obtained through the diet, mainly from animal products such as meat, fish, eggs and milk.

Vegetarians and vegans have an increased risk of deficiency and should ensure adequate intake, either through fortified foods or dietary supplements.

Vitamin B12 is crucial for the production and maturation of red blood cells, which enable oxygen transport in the blood. It plays a central role in DNA synthesis, cell division and nervous system health. It is particularly important for the myelin sheath, which protects nerve fibres and ensures normal nerve cell function. It also supports the formation of new cells in rapidly growing tissues such as bone marrow and skin.

Iron fulfils numerous important functions in the body, particularly oxygen transport and supporting the immune system. It is an essential component of many enzymes and plays a key role in biochemical processes such as DNA synthesis and cell division. Iron is crucial for the formation of haemoglobin, which transports oxygen from the lungs to the tissues, and for myoglobin, which stores oxygen in the muscles.

Ferritin acts as the main storage form for iron in the body and is found mainly in the liver, spleen, bone marrow and blood. It enables the safe storage and demand-based release of iron.

Ferritin concentration in the blood serves as an important marker for iron status: Low values indicate iron deficiency and possible anaemia, while high values may indicate excess iron or inflammation. Thus, ferritin plays a central role in iron metabolism and is an essential biomarker for assessing iron balance.

What is measured?

The following parameters are measured in the laboratory for the Nutrients combination test: 25-OH vitamin D, vitamin B12, ferritin, folic acid (vitamin B9) and magnesium.

Which test method is used?

The chemiluminescent microparticle immunoassay (CMIA) is used to measure 25-OH vitamin D, vitamin B12, ferritin and folic acid. This method is based on the binding of antibodies to the respective substance, which triggers a chemiluminescent reaction. The intensity of the emitted light is directly proportional to the concentration of the respective nutrient.

Magnesium, however, is measured using a colorimetric method with chlorophosphonazo III, in which a coloured reaction occurs, the intensity of which is proportional to the magnesium concentration.